Radiation Therapy Compared With Combination Chemotherapy in Treating Patients With Cancer of the Uterus

Completed · Phase 3

Conditions studied: Sarcoma

In brief

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether radiation therapy is more effective than combination chemotherapy in treating patients with cancer of the uterus. PURPOSE: This randomized phase III trial is studying radiation therapy to see how well it works compared to combination chemotherapy in treating patients with cancer of the uterus.

Key facts

Study ID

NCT00002546

Run by

Gynecologic Oncology Group

People needed

216

Starts

1993-12-01

Last updated by the study team

2016-02-11

Who can join

Age: 21 and older, up to 120. Sex: female. Healthy volunteers: not accepted.

Where it is running

• CCOP - Western Regional, Arizona — Phoenix, Arizona, United States
• Women's Cancer Center - Los Gatos — Los Gatos, California, United States
• Chao Family Comprehensive Cancer Center at University of California Irvine Cancer Center — Orange, California, United States
• University of Colorado Cancer Center at University of Colorado Health Sciences Center — Denver, Colorado, United States
• CCOP - Christiana Care Health Services — Newark, Delaware, United States
• Walter Reed Army Medical Center — Washington D.C., District of Columbia, United States
• University of Miami Sylvester Comprehensive Cancer Center — Miami, Florida, United States
• Rush University Medical Center — Chicago, Illinois, United States
• MBCCOP - University of Illinois at Chicago — Chicago, Illinois, United States
• University of Chicago Cancer Research Center — Chicago, Illinois, United States
• CCOP - Central Illinois — Decatur, Illinois, United States
• CCOP - Evanston — Evanston, Illinois, United States
• Study site — Hinsdale, Illinois, United States
• CCOP - Carle Cancer Center — Urbana, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• CCOP - Northern Indiana CR Consortium — South Bend, Indiana, United States
• Saint Joseph Regional Medical Center — South Bend, Indiana, United States
• Holden Comprehensive Cancer Center at University of Iowa — Iowa City, Iowa, United States
• Cancer Center at Tufts - New England Medical Center — Boston, Massachusetts, United States
• UMASS Memorial Cancer Center - University Campus — Worcester, Massachusetts, United States
• CCOP - Michigan Cancer Research Consortium — Ann Arbor, Michigan, United States
• Barbara Ann Karmanos Cancer Institute — Detroit, Michigan, United States
• CCOP - Grand Rapids — Grand Rapids, Michigan, United States
• CCOP - Kalamazoo — Kalamazoo, Michigan, United States
• University of Alabama at Birmingham Comprehensive Cancer Center — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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