Radiation Therapy Plus Chemotherapy in Treating Patients With Supratentorial Glioblastoma Multiforme

Completed · Phase 3

Conditions studied: Brain and Central Nervous System Tumors

In brief

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Chemotherapy uses different ways to stop tumor cells from dividing so they stop growing or die. Combining radiation therapy with chemotherapy may kill more tumor cells. PURPOSE: Randomized phase III trial to study the effectiveness of radiation therapy and carmustine in treating patients who have supratentorial glioblastoma multiforme.

Key facts

Study ID

NCT00002545

Run by

Radiation Therapy Oncology Group

People needed

200

Starts

1994-02-01

Last updated by the study team

2013-08-13

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• University of Alabama Comprehensive Cancer Center — Birmingham, Alabama, United States
• Huntsville Hospital System — Huntsville, Alabama, United States
• Urology Associates - Mobile AL — Mobile, Alabama, United States
• MBCCOP - University of South Alabama — Mobile, Alabama, United States
• Alabama Oncology, LLC — Montgomery, Alabama, United States
• Radiation Oncology Associates of West Alabama — Tuscallosa, Alabama, United States
• Providence Cancer Therapy Center — Anchorage, Alaska, United States
• St. Joseph's Hospital and Medical Center — Phoenix, Arizona, United States
• Arizona Cancer Center — Tucson, Arizona, United States
• Providence Saint Joseph Medical Center - Burbank — Burbank, California, United States
• Mount Diablo Medical Center — Concord, California, United States
• California Cancer Center — Fresno, California, United States
• Saint Agnes Cancer Center — Fresno, California, United States
• Glendale Memorial Hospital and Health Center — Glendale, California, United States
• Sutter Health Western Division Cancer Research Group — Greenbrae, California, United States
• Loma Linda University Medical Center — Loma Linda, California, United States
• Veterans Affairs Medical Center - Long Beach — Long Beach, California, United States
• Kaiser Permanente Medical Center - Los Angeles — Los Angeles, California, United States
• USC/Norris Comprehensive Cancer Center — Los Angeles, California, United States
• Jonsson Comprehensive Cancer Center, UCLA — Los Angeles, California, United States
• Beckman Research Institute, City of Hope — Los Angeles, California, United States
• Veterans Affairs Outpatient Clinic - Martinez — Martinez, California, United States
• CCOP - Bay Area Tumor Institute — Oakland, California, United States
• Cancer Care Center — Pomona, California, United States
• Veterans Affairs Medical Center - Birmingham — Birmingham, Alabama, United States

Full record on ClinicalTrials.gov

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