Screening for Prostate Cancer in Older Patients (PLCO Screening Trial)
Running, not enrolling · Not applicable
Conditions studied: Prostate Carcinoma
In brief
This clinical trial studies whether screening methods used to diagnose cancer of the prostate, lung, colon, rectum, or ovaries can reduce deaths from these cancers. Screening tests may help doctors find cancer cells early and plan better treatment for prostate cancer.
Key facts
- Study ID
- NCT00002540
- Run by
- National Cancer Institute (NCI)
- People needed
- 76685
- Starts
- 1993-11-16
- Expected to finish
- 2027-06-30
- Last updated by the study team
- 2026-07-24
Who can join
Age: 55 and older, up to 74. Sex: male. Healthy volunteers: not accepted.
You may not qualify if…
- Men who at the time of randomization are less than 55 or greater than or equal to 75 years of age
- Individuals undergoing treatment for cancer at this time, excluding basal-cell and squamous-cell skin cancer
- Individuals with known prior cancer of the colon, rectum, lung, prostate
- This includes primary or metastatic PLCO cancers
- Individuals with previous surgical removal of the entire colon, one lung, or the entire prostate
- Individuals who are participating in another cancer screening or cancer primary prevention trial
- Males who have taken Proscar/Propecia/finasteride in the past 6 months
- NOTE: Individuals who are already enrolled in the trial when their physician prescribes finasteride are not prevented from taking this medication. As a result, these participants will continue to be screened and followed just as those participants who are not on finasteride.
- NOTE: Men who are taking Tamoxifen are not excluded from any part of the PLCO Screening Trial.
- Individuals who are unwilling or unable to sign the informed consent form
- Males who have had more than one PSA blood test in the past three years
- Individuals who have had a colonoscopy, sigmoidoscopy, or barium enema in the past three years
Where it is running
- National Institutes of Health Clinical Center — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
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