Radiation Therapy and Chemotherapy in Treating Patients With Head and Neck Cancer

Completed · Phase 3

Conditions studied: Carcinoma of Unknown Primary, Head and Neck Cancer

In brief

RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known whether combining mitomycin or porfiromycin with radiation therapy is more effective in treating patients with head and neck cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy plus either mitomycin or porfiromycin in treating patients with head and neck cancer.

Key facts

Study ID

NCT00002507

Run by

Yale University

Starts

1992-11-01

Expected to finish

2002-10-01

Last updated by the study team

2013-07-25

Who can join

Age: 20 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Yale Comprehensive Cancer Center — New Haven, Connecticut, United States

Full record on ClinicalTrials.gov

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