Radiation Therapy With or Without Chemotherapy in Treating Patients With Advanced Cancer of the Larynx

Completed · Phase 3

Conditions studied: Head and Neck Cancer

In brief

RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known if chemotherapy plus radiation therapy is more effective than radiation therapy alone in treating patients with advanced cancer of the larynx. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without chemotherapy in treating patients with advanced cancer of the larynx.

Key facts

Study ID

NCT00002496

Run by

Radiation Therapy Oncology Group

Starts

1992-08-01

Expected to finish

2013-11-01

Last updated by the study team

2014-01-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

Where it is running

• CCOP - Colorado Cancer Research Program, Inc. — Denver, Colorado, United States
• H. Lee Moffitt Cancer Center and Research Institute — Tampa, Florida, United States
• Veterans Affairs Medical Center - Atlanta (Decatur) — Decatur, Georgia, United States
• CCOP - Illinois Oncology Research Association — Peoria, Illinois, United States
• CCOP - Carle Cancer Center — Urbana, Illinois, United States
• Indiana University Cancer Center — Indianapolis, Indiana, United States
• Veterans Affairs Medical Center - Indianapolis (Roudebush) — Indianapolis, Indiana, United States
• CCOP - Iowa Oncology Research Association — Des Moines, Iowa, United States
• New England Medical Center Hospital — Boston, Massachusetts, United States
• Beth Israel Deaconess Medical Center — Boston, Massachusetts, United States
• CCOP - Kalamazoo — Kalamazoo, Michigan, United States
• CCOP - Metro-Minnesota — Saint Louis Park, Minnesota, United States
• Veterans Affairs Medical Center - East Orange — East Orange, New Jersey, United States
• CCOP - Northern New Jersey — Hackensack, New Jersey, United States
• Ireland Cancer Center — Cleveland, Ohio, United States
• Hahnemann University Hospital — Philadelphia, Pennsylvania, United States
• University of Pittsburgh Cancer Institute — Pittsburgh, Pennsylvania, United States
• Pretoria Academic Hospital — Pretoria, South Africa

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.