A Study to Compare the Effectiveness of Two Anti-HIV Drug Combinations

Completed · Not applicable

Conditions studied: HIV Infections

In brief

The purpose of this study is to compare two different anti-HIV drug combinations, one that contains nelfinavir (NFV) and one that does not. The best dosing schedule for indinavir (IDV) also will be studied.

Key facts

Study ID

NCT00002430

Run by

Merck Sharp & Dohme LLC

People needed

220

Last updated by the study team

2005-06-24

Who can join

Age: 16 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• You may be eligible for this study if you:
• Are HIV positive.
• Have a viral load (level of HIV in your blood) of at least 10,000 copies/ml within 45 days of study entry.
• Have a CD4 cell count of at least 100 cells/mm3 within 45 days of study entry.
• Have a normal chest X-ray.
• Have never taken protease inhibitors or 3TC.
• Are 16 years of age or older.
• Agree to practice sexual abstinence or use barrier methods of birth control (e.g., condoms).

You may not qualify if…

• You will not be eligible for this study if you:
• Have an active opportunistic (AIDS-related) infection or cancer.
• Have certain types of Kaposi's sarcoma.
• Have hepatitis.
• Have chronic diarrhea.
• Have a history of certain medical conditions.
• Are allergic to any of the study medications.
• Are taking certain medications.
• Are pregnant or breast-feeding.

Where it is running

• Univ of Alabama School of Med — Montgomery, Alabama, United States
• Ocean View Internal Medicine — Long Beach, California, United States
• AIDS Healthcare Foundation — Los Angeles, California, United States
• Tower ID Med Associates — Los Angeles, California, United States
• Oasis Clinic / King Drew Med Ctr — Los Angeles, California, United States
• Robert Scott MD — Oakland, California, United States
• AIDS Community Research Consortium — Redwood City, California, United States
• Saint Francis Mem Hosp / HIV Care Unit — San Francisco, California, United States
• Pacific Horizons Med Group — San Francisco, California, United States
• Kaiser Foundation Hospital — San Francisco, California, United States
• Harbor - UCLA Med Ctr — Torrance, California, United States
• Denver Public Health Dept — Denver, Colorado, United States
• Blick Med Associates — Stamford, Connecticut, United States
• Physicans Home Service — Washington D.C., District of Columbia, United States
• IDC Research Initiative — Altamonte Springs, Florida, United States
• Univ of Miami School of Medicine — Miami, Florida, United States
• Hillsborough County Health Dept — Tampa, Florida, United States
• Emory Univ — Atlanta, Georgia, United States
• Harold Katner MD — Macon, Georgia, United States
• Thomas Coffman MD — Boise, Idaho, United States
• Chicago Ctr for Clinical Research — Chicago, Illinois, United States
• Northwestern Univ Med Ctr — Chicago, Illinois, United States
• Univ of Illinois — Chicago, Illinois, United States
• Kentucky Clinical Research — Lexington, Kentucky, United States
• Louisiana State Univ Med Ctr / Tulane Med School — New Orleans, Louisiana, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.