A Comparison of Valganciclovir and Ganciclovir in the Treatment of Cytomegalovirus (CMV) of the Eyes

Completed · Phase 3

Conditions studied: Cytomegalovirus Retinitis, HIV Infections

In brief

To investigate the efficacy and safety of RS-79070 when used as induction therapy in patients with newly diagnosed peripheral retinitis. To assess the effects of induction and maintenance level dosing of RS-79070 on CMV viral load, estimated by plasma CMV PCR. To assess the pharmacokinetics of ganciclovir following administration of RS-79070 in the target population.

Key facts

Study ID

NCT00002377

Run by

Hoffmann-La Roche

Starts

1997-01-01

Expected to finish

2002-12-01

Last updated by the study team

2017-05-17

Who can join

Age: 14 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Documented AIDS diagnosis
• Newly diagnosed peripheral CMV retinitis
• More than 3 weeks of previous therapy for CMV retinitis

Where it is running

• Univ of California / Irvine — Irvine, California, United States
• Univ of California / San Diego / Dept of Pediatrics — La Jolla, California, United States
• Univ of California / San Diego Treatment Ctr — San Diego, California, United States
• Davies Med Ctr / Institute for HIV Research — San Francisco, California, United States
• Kaiser Permanente Med Ctr — San Francisco, California, United States
• QUEST Clinical Research — San Francisco, California, United States
• Dr Alan Palestine — Washington D.C., District of Columbia, United States
• Univ of Miami School of Medicine — Miami, Florida, United States
• Emory Eye Clinic — Atlanta, Georgia, United States
• New England Med Ctr — Boston, Massachusetts, United States
• New York Univ Med Ctr — New York, New York, United States
• St Luke's - Roosevelt Hosp Ctr / Div of Infect Dis — New York, New York, United States
• New York Hosp - Cornell Med Ctr — New York, New York, United States
• Duke Univ Eye Ctr — Durham, North Carolina, United States
• Austin Infectious Disease Consultants — Austin, Texas, United States
• St Pauls Hosp — Vancouver, British Columbia, Canada
• The Toronto Hosp / Dept of Infectious Disease — Toronto, Ontario, Canada
• Montreal Chest Institute — Montreal, Quebec, Canada
• Royal Victoria Hosp — Montreal, Quebec, Canada

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.