The Safety and Effectiveness of Clarithromycin in the Prevention of Mycobacterium Avium Complex (MAC) Infection in HIV-Infected Patients

Completed · Not applicable

Conditions studied: Mycobacterium Avium-intracellular Infection, HIV Infections

In brief

To determine whether clarithromycin is safe and effective in preventing disseminated Mycobacterium avium Complex in HIV-infected patients with CD4 counts \<= 100 cells/mm3.

Key facts

Study ID

NCT00002336

Run by

Abbott

Starts

1992-11-01

Expected to finish

1994-11-01

Last updated by the study team

2015-01-16

Who can join

Age: 12 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients must have:
• HIV infection.
• CD4 count <= 100 cells/mm3.
• No evidence of MAC.
• Life expectancy of at least 6 months.

You may not qualify if…

• Concurrent Medication:
• Excluded:
• Certain restricted drugs (details not available).
• Patients with the following prior conditions are excluded:
• History of allergy or hypersensitivity to macrolides. Active substance abuse or other conditions that would affect study compliance.

Where it is running

• Univ of Arizona / Health Science Ctr — Tucson, Arizona, United States
• California Med Research Group — Fresno, California, United States
• HIV Research Group — San Diego, California, United States
• Saint Francis Mem Hosp — San Francisco, California, United States
• Kaiser Permanente Med Ctr — San Francisco, California, United States
• Santa Clara Valley Med Ctr — San Jose, California, United States
• TheraFirst Med Ctrs Inc — Fort Lauderdale, Florida, United States
• Dr Nelson Zide — Hollywood, Florida, United States
• Infectious Disease Research Institute Inc — Tampa, Florida, United States
• Indiana Univ Hosp — Indianapolis, Indiana, United States
• Saint Vincent's Hosp and Med Ctr — New York, New York, United States
• SUNY / Health Sciences Ctr at Syracuse — Syracuse, New York, United States
• New York Med College / Westchester County Med Ctr — Valhalla, New York, United States
• Nalle Clinic — Charlotte, North Carolina, United States
• Westover Heights Clinic — Portland, Oregon, United States
• Univ of Tennessee — Memphis, Tennessee, United States
• Vanderbilt Univ — Nashville, Tennessee, United States
• Univ of Texas Southwestern Med Ctr of Dallas — Dallas, Texas, United States
• Houston Veterans Administration Med Ctr — Houston, Texas, United States
• Audie L Murphy Veterans Administration Hosp — San Antonio, Texas, United States
• Salem Veterans Administration Med Ctr — Salem, Virginia, United States
• Dr Alan D Tice / Infections Ltd — Tacoma, Washington, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.