Prospective Comparison of Ampicillin / Amoxicillin Versus Ceftriaxone for the Treatment of Salmonella Infections in AIDS Patients

Completed · Not applicable

Conditions studied: HIV Infections, Salmonella Infections

In brief

To compare the effectiveness of standard treatment with parenteral ampicillin and oral amoxicillin compared to initial daily therapy with ceftriaxone followed by 3 times weekly suppressive treatment for salmonella infections in AIDS patients.

Key facts

Study ID

NCT00002052

Run by

University of Southern California

Last updated by the study team

2005-06-24

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may not qualify if…

• Co-existing Condition:
• Patients with the following are excluded:
• Type I hypersensitivity to beta-lactam antibiotics.
• Not expected to survive 12 weeks.
• In a coma or with other central nervous system (CNS) impairment.
• Patients with the following are excluded:
• Type I hypersensitivity to beta-lactam antibiotics.
• Not expected to survive 12 weeks.
• In a coma or with other central nervous system (CNS) impairment.
• Prior Medication:
• Excluded within 48 hours of study entry:
• Treatment with an antibiotic active in vitro against Salmonella.
• HIV infection, AIDS, or AIDS related complex (ARC).
• Salmonella bacteremia or positive stool culture in patient with 3 or more stools per day.

Where it is running

• Los Angeles County - USC Med Ctr — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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