Determination of Kidney Function
Stopped early
Conditions studied: Kidney Disease, Proteinuria, Autoimmune / Connective Tissue Diseases
In brief
Much more about kidney disorders can be learned by determining kidney function. This research proposes to study the kidneys function by several parameters known as glomerular filtration rate (GFR), Renal Plasma Flow (RPF), and Glomerular Capillary Wall Permselectivity. The study will select patients suffering from different types of kidney diseases. These patients will be selected based on the presence of significant amounts of protein in their urine (proteinuria). Standard blood and urine tests are often unable to provide completely accurate information about the kidney. In order for researchers to have a more accurate idea of kidney function, they will use alternative tests. Test materials (para aminohippurate and inulin) will be injected into patients veins that provides information based on their filtration through the kidneys....
Key facts
- Study ID
- NCT00001978
- Run by
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
- People needed
- 456
- Starts
- 1989-10-11
- Expected to finish
- 2020-10-02
- Last updated by the study team
- 2020-10-08
Who can join
Age: 7 and older. Sex: any. Healthy volunteers: accepted.
You may not qualify if…
- Pregnant females or nursing mothers will be excluded from all aspects of this study (at least until the infant is stable on a regimen of formula feeding).
- Patients will not receive a test material if there is a history of allergy to that material.
- Patients with a history of bronchial asthma or allergy to iodine-containing contrast material will not receive iothalamate.
Where it is running
- National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States
Full record on ClinicalTrials.gov
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