Cell Selection for Bone Marrow Transplants to Prevent Graft-Versus-Host-Disease

Completed

Conditions studied: Graft vs Host Disease, Hematologic Neoplasm

In brief

Blood contains different kinds of cells, white blood cells, red blood cells, and platelets. In order to treat certain diseases, specific cell types can be removed from blood and transplanted into patients. The process of removing white blood cells for the treatment of leukemia is called apheresis. This study will make available blood cell collections from volunteers genetically matched to various degrees with recipients in order to test and, if necessary, refine the process of removing white blood cell T-lymphocytes....

Key facts

Study ID

NCT00001872

Run by

National Heart, Lung, and Blood Institute (NHLBI)

People needed

14

Starts

1999-02-02

Expected to finish

2018-03-02

Last updated by the study team

2019-12-17

Who can join

Age: 18 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may not qualify if…

• Pregnancy or lactation.
• HLA type unknown.
• More than one haplotype mismatch with patient.
• History of any immunosuppressive disease.
• History of chronic viral antigenic stimulus.
• Venous access inadequate.

Where it is running

• National Institutes of Health Clinical Center, 9000 Rockville Pike — Bethesda, Maryland, United States

Full record on ClinicalTrials.gov

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