A Study of an Adherence Plan to Help HIV-Positive Patients Take Their First Anti-HIV Medications Correctly
Completed · Phase 2
Conditions studied: HIV Infections
In brief
The purpose of this study is to see if observed therapy can help HIV-positive patients stick to their anti-HIV medication schedule. Observed therapy means that a nurse will watch patients take their medications to make sure that they take them correctly. It is very important that HIV-positive patients take their anti-HIV medications correctly so they get the best possible benefit from them. Taking the drugs correctly, called "adherence," may keep HIV virus levels in the blood (viral load) low for a longer time. Adherence can also slow the development of drug resistance, and this is especially important in patients with early HIV infection who are just beginning treatment. However, anti-HIV medication schedules are often complicated, and many patients have difficulty remembering to take their drugs at the correct time. This study will look at the effectiveness of a plan to help patients with this problem.
Key facts
- Study ID
- NCT00001122
- Run by
- National Institute of Allergy and Infectious Diseases (NIAID)
- People needed
- 74
- Last updated by the study team
- 2011-03-02
Who can join
Age: 13 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Patients may be eligible for this study if they:
- Are HIV-positive.
- Are at least 13 years old (consent is required if you are under 18).
- Have a CD4 count of at least 200 cells/mm3 within 30 days of study entry.
- Have never taken anti-HIV drugs.
- Agree to practice effective methods of birth control.
You may not qualify if…
- Patients will not be eligible for this study if they:
- Have cancer (except for Kaposi's sarcoma) that requires treatment.
- Have a history of hepatitis or pancreatitis.
- Have peripheral neuropathy.
- Have an alcohol abuse problem.
- Are pregnant or breast-feeding.
- Are taking certain medications, such as rifabutin, rifampin, interleukin, or chemotherapy.
Where it is running
- UCSD — San Diego, California, United States
- Univ of Texas Southwestern Med Ctr — Dallas, Texas, United States
Full record on ClinicalTrials.gov
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