The Effects of Staggered Dosing on Interactions Between Paired Combinations of Nelfinavir, Ritonavir, and Saquinavir

Completed · Not applicable

Conditions studied: HIV Infections

In brief

The purpose of this study is to see if staggering doses of nelfinavir, ritonavir, and saquinavir has any effect on the interactions between these drugs.

Key facts

Study ID

NCT00000898

Run by

National Institute of Allergy and Infectious Diseases (NIAID)

People needed

18

Expected to finish

2000-05-01

Last updated by the study team

2021-10-29

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients must have:
• Absence of HIV-1 infection as documented by any licensed ELISA test kit within 14 days prior to study entry.

You may not qualify if…

• Co-existing Condition:
• Patients with the following symptoms and conditions are excluded:
• Any medical condition that, in the opinion of the investigator, would interfere with the patient's ability to participate in this protocol.
• Patients with the following prior conditions and symptoms are excluded:
• History of chronic illness such as hypertension, coronary artery disease, arthritis, diabetes, or any chronic gastrointestinal conditions that might interfere with drug absorption.

Where it is running

• San Francisco Gen Hosp — San Francisco, California, United States
• Univ of California/ San Francisco / Dept of Medicine — San Francisco, California, United States
• Stanford Univ Med Ctr — Stanford, California, United States
• Johns Hopkins Hosp — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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