Treatment With Combinations of Several Antiviral Drugs in Infants and Young Children With HIV Infection

Completed · Phase 2

Conditions studied: HIV Infections

In brief

This trial tests the safety and effectiveness of the early use of combinations of anti-HIV drugs in HIV-infected infants and young children in an effort to block virus growth and preserve normal immune functions. Various anti-HIV drug combinations need to be tested in order to find the best way to treat infants and children who have been infected with HIV during birth.

Key facts

Study ID

NCT00000872

Run by

National Institute of Allergy and Infectious Diseases (NIAID)

People needed

55

Expected to finish

2005-01-01

Last updated by the study team

2021-11-04

Who can join

Age: 0 and older, up to 2. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Children may be eligible for this study if they:
• Are 15 days to 2 years old.
• Have consent of parent or legal guardian.
• Are HIV-positive.

You may not qualify if…

• Children will not be eligible for this study if they:
• Have certain infections which require treatment during the study.
• Have received certain medications.

Where it is running

• Univ. of Florida College of Medicine-Dept of Peds, Div. of Immunology, Infectious Diseases & Allergy — Gainesville, Florida, United States
• Tulane/LSU Maternal/Child CRS — New Orleans, Louisiana, United States
• Univ. of Maryland Med. Ctr., Div. of Ped. Immunology & Rheumatology — Baltimore, Maryland, United States
• Johns Hopkins Hosp. & Health System - Dept. of Peds., Div. of Infectious Diseases — Baltimore, Maryland, United States
• BMC, Div. of Ped Infectious Diseases — Boston, Massachusetts, United States
• Baystate Health, Baystate Med. Ctr. — Springfield, Massachusetts, United States
• WNE Maternal Pediatric Adolescent AIDS CRS — Worcester, Massachusetts, United States
• Univ. of Mississippi Med. Ctr Children's Hosp. — Detroit, Michigan, United States
• Nyu Ny Nichd Crs — New York, New York, United States
• The Children's Hosp. of Philadelphia IMPAACT CRS — Philadelphia, Pennsylvania, United States
• Texas Children's Hosp. CRS — Houston, Texas, United States
• Children's Hosp. of the King's Daughters, Infectious Disease — Norfolk, Virginia, United States

Full record on ClinicalTrials.gov

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