Intracellular Pharmacokinetics of Zidovudine Triphosphate in Maternal and Infant Cord Blood Mononuclear Cells.

Completed

Conditions studied: HIV Infections, Pregnancy

In brief

To determine the levels of zidovudine triphosphate ( AZT-TP ) in maternal and fetal cord blood mononuclear cells. To determine the ratio of AZT-TP to endogenous nucleoside triphosphate levels in maternal and fetal cells. To determine the extent of drug transfer through the feto/placental unit.

Key facts

Study ID

NCT00000830

Run by

National Institute of Allergy and Infectious Diseases (NIAID)

People needed

24

Last updated by the study team

2005-06-24

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

Where it is running

• Univ of Medicine & Dentistry of New Jersey / Univ Hosp — Newark, New Jersey, United States
• Bellevue Hosp / New York Univ Med Ctr — New York, New York, United States
• Mount Sinai Med Ctr / Pediatrics — New York, New York, United States
• Regional Med Ctr at Memphis — Memphis, Tennessee, United States
• Saint Jude Children's Research Hosp of Memphis — Memphis, Tennessee, United States
• San Juan City Hosp — San Juan, Puerto Rico

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.