Action to Control Cardiovascular Risk in Diabetes (ACCORD)
Completed · Phase 3 · Has a placebo group
Conditions studied: Atherosclerosis, Cardiovascular Diseases, Hypercholesterolemia, Hypertension, Diabetes Mellitus, Type 2, Diabetes Mellitus, Coronary Disease
In brief
The purpose of this study is to prevent major cardiovascular events (heart attack, stroke, or cardiovascular death) in adults with type 2 diabetes mellitus using intensive glycemic control, intensive blood pressure control, and multiple lipid management.
Key facts
- Study ID
- NCT00000620
- Run by
- National Heart, Lung, and Blood Institute (NHLBI)
- People needed
- 10251
- Starts
- 1999-09-01
- Expected to finish
- 2012-12-01
- Last updated by the study team
- 2016-11-22
Who can join
Age: 40 and older, up to 79. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosed with type 2 diabetes mellitus, as determined by the new American Diabetes Association guidelines, which include a fasting plasma glucose level greater than 126 mg/dl (7.0 mmol/l), or a 2-hour postload value in the oral glucose tolerance test of greater than 200 mg/dl, with confirmation by a retest
- For participants aged 40 years or older, history of CVD (heart attack, stroke, history of coronary revascularization, history of peripheral or carotid revascularization, or demonstrated angina)
- For participants aged 55 years or older, a history of CVD is not required, but participant must be considered to be at high risk for experiencing a CVD event due to existing CVD, subclinical disease, or 2+ CVD risk factors
- HbA1c 7.5%-9% (if on more drugs) or 7.5%-11% (if on fewer drugs)
Where it is running
- Minneapolis Medical Research Foundation — Minneapolis, Minnesota, United States
- Columbia University — New York, New York, United States
- Wake Forest University — Winston-Salem, North Carolina, United States
- Case Western Reserve University — Cleveland, Ohio, United States
- Veterans Affairs — Memphis, Tennessee, United States
- University of Washington — Seattle, Washington, United States
- McMaster University — Hamilton, Ontario, Canada
Full record on ClinicalTrials.gov
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