Osteoporosis Prevention in Preadolescent Girls

Completed · Phase 2

Conditions studied: Osteoporosis

In brief

This study will test an osteoporosis prevention program aimed at preadolescent girls between the ages of 10 and 12 who have not yet started their menstrual periods. Girls in this age group are adding large amounts of new bone to their skeletons. Adding more bone at this time of life can reduce a person's chances of developing osteoporosis (thinning bones) in later years. We will look at how this osteoporosis prevention program affects the amount of calcium in the girls' diets, the amount of weight-bearing exercise they do, and their bone mass measured using ultrasound testing of the heel.

Key facts

Study ID

NCT00000413

Run by

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

People needed

340

Starts

1998-07-01

Expected to finish

2002-06-01

Last updated by the study team

2006-12-29

Who can join

Age: 9 and older, up to 13. Sex: female. Healthy volunteers: accepted.

You may qualify if…

• 9- and 10-year-old premenarchal girls (girls who have not started their periods).

You may not qualify if…

• Comorbid conditions or medications that are associated with decreased bone density such as the following: corticosteroids; anticonvulsants; thiazide diuretics; history of cancer; Type I diabetes; thyrotoxicosis; hyperparathyroidism; Cushing's syndrome; juvenile rheumatoid arthritis; connective tissue disease or hemolytic anemia; asthma which may limit ability to participate in the exercise intervention; known history of dietary disorder, including anorexia, bulimia or lactose intolerance; postmenarchal.

Where it is running

• University Hospitals of Cleveland — Cleveland, Ohio, United States

Full record on ClinicalTrials.gov

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