Infusion Laboratory: Protocol 5 (Flupenthixol) - 14

Status unconfirmed · Phase 1

Conditions studied: Cocaine-Related Disorders

In brief

The purpose of this study is to evaluate clinical safety issues pertaining to flupenthixol, to cocaine, and to their interaction, and to determine how pretreatment with flupenthixol modifies the subjective as well as physiological effects of cocaine. Taken together, these relatively D-1 selective agents can help determine the extent to which DA-1 binding affects the reinforcing effects of stimulants.

Key facts

Study ID

NCT00000349

Run by

National Institute on Drug Abuse (NIDA)

People needed

0

Last updated by the study team

2017-01-11

Who can join

Age: 21 and older, up to 50. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• M/F, ages 21-50. Meet DSM-IV criteria for cocaine dependence. Agree to conditions of the study and sign informed consent.

You may not qualify if…

• Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nuring women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical condtions that deem participation to be unsafe.

Where it is running

• Friends Research Institute — Los Angeles, California, United States

Full record on ClinicalTrials.gov

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