The Effects of Sex Hormones on Cognition and Mood in Older Adults

Stopped early · Not applicable

Conditions studied: Cognition Disorders, Mood Disorders

In brief

This study is investigating the effects of hormone replacement therapy on memory, mental abilities and mood in older adults aged 65-90. During the nine month long study, men will take testosterone for three months and women will take estrogen for three months. At four points during the study (once every three months), participants will complete a test battery and have blood drawn.

Key facts

Study ID

NCT00000175

Run by

National Institute on Aging (NIA)

Expected to finish

2005-06-01

Last updated by the study team

2009-12-11

Who can join

Age: 65 and older, up to 90. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Women and men aged 65-90 who have not received hormone replacement for the last three months.

You may not qualify if…

• Previous head injury with loss of consciousness for more than one hour.
• Men with a history of prostate cancer.
• Men on testosterone replacement within the past three months.
• Women with a history of breast or uterine cancer.
• Women on estrogen replacement within the past three months.

Where it is running

• Gerontology Research Center — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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