Body Water Content in Cyanotic Congenital Heart Disease

Completed

Conditions studied: Heart Defects, Congenital

In brief

Adults with cyanotic congenital heart disease have elevated levels of plasma proatrial natruretic peptide (proANP) which most likely results in chronic dehydration, leading to reduced oxygen transport to tissues and shortness of breath with activity. The purpose of this study is to characterize adults with cyanotic congenital heart defects with respect to their body composition (water and fat-free mass) and resting metabolic rates. The study consists of several measures of how much body water, fat and lean tissue a subject has, and measures the number of calories the subject's body uses at rest. Adult subjects with cyanotic congenital heart disease will be recruited along with healthy noncyanotic control subjects matched for age, gender, and body weight.

Key facts

Study ID

NCT00000107

Run by

National Center for Research Resources (NCRR)

Last updated by the study team

2005-06-24

Who can join

Age: 17 and older, up to 60. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Resting blood pressure below 140/90

Where it is running

• University of Vermont — Burlington, Vermont, United States

Full record on ClinicalTrials.gov

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