University of Louisville/James Graham Brown Cancer Center

Louisville, Kentucky 40202-5700

4 studies enrolling now · 37 studies all time

What they study most

AML, Advanced Cutaneous Melanoma, Advanced Solid Tumors, Advanced Solid Tumors Cancer, Bladder Cancer, Brain Metastases, Brain Metastases From Non-small Cell Lung Cancer (NSCLC), Breast Cancer, Cancer, Carcinoma, Non-Small-Cell Lung, Cardiac Toxicity, Cardiovascular Complications

Studies at this site

• Pan Tumor Rollover Study — Recruiting now
• Study to Investigate Lifileucel Regimen Plus Pembrolizumab Compared With Pembrolizumab Alone in Participants With Untreated Advanced Melanoma. — Recruiting now
• A Study to Assess the Safety, Tolerability, and Efficacy of NDI-219216 in Patients With Advanced Solid Tumors. — Recruiting now
• Observational Basket Trial to Collect Tissue to Develop and Train a Live Tumor Diagnostic Platform (ELEPHAS-02) — Running, not enrolling
• A Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder — Completed
• Phase II Trial of Adjuvant Cisplatin and Radiation With Pembrolizumab in Resected Head and Neck Squamous Cell Carcinoma — Running, not enrolling
• Study Evaluating Tarlatamab After Chemoradiotherapy in Limited-Stage Small-Cell Lung Cancer (LS-SCLC) — Running, not enrolling
• Expanded Access Program of AMTAGVI That is Out of Specification for Commercial Release — Available (expanded access)
• Pivotal, Randomized, Open-label Study of Optune® (Tumor Treating Fields) Concomitant With RT & TMZ for the Treatment of Newly Diagnosed GBM — Completed
• Evaluation of Lymphodepletion With ALLO-647 in Adults With R/R Large B Cell Lymphoma Receiving ALLO-501A Allogeneic CAR T Cell Therapy — Stopped early
• Expanded Access Program (EAP) for Ciltacabtagene Autoleucel (Cilta-Cel) Out-of-Specification (OOS) in Participants With Multiple Myeloma — Available (expanded access)
• Evaluation of Lasofoxifene Versus Fulvestrant in Advanced or Metastatic ER+/HER2- Breast Cancer With an ESR1 Mutation — Completed
• SBRT +/- Pembrolizumab in Patients With Local-Regionally Recurrent or Second Primary Head and Neck Carcinoma — Running, not enrolling
• Unresectable Stage IIIA/IIIB Non-small Cell Lung Cancer (NSCLC) — Completed
• Study Assessing the Efficacy and Safety of Alpelisib Plus Fulvestrant or Letrozole, Based on Prior Endocrine Therapy, in Patients With PIK3CA Mutant, HR+, HER2- Advanced Breast Cancer Who Have Progressed on or After Prior Treatments — Completed
• Pivotal, Open-label, Randomized Study of Radiosurgery With or Without Tumor Treating Fields (TTFields) for 1-10 Brain Metastases From Non-small Cell Lung Cancer (NSCLC). — Completed
• AMG 404 in Patients With Advanced Solid Tumors — Completed
• Talimogene Laherparepvec With Pembrolizumab in Melanoma Following Progression on Prior Anti-PD-1 Based Therapy (MASTERKEY-115) (Mk-3475-A07/KEYNOTE-A07). — Completed
• Phase II Randomized Trial of mFOLFIRINOX +/- Ramucirumab in Advanced Pancreatic Cancer — Completed
• BXQ-350 in Newly Diagnosed Metastatic Colorectal Carcinoma — Running, not enrolling
• SGI-110 in the Treatment of Advanced Hepatocellular Carcinoma (HCC) — Completed
• NT-I7 in Combination With Nivolumab in Advanced Gastric, Gastro-Esophageal Junction or Esophageal Adenocarcinoma — Stopped early
• Trial to Evaluate the Safety of Talimogene Laherparepvec Injected Into Tumors Alone and in Combination With Systemic Pembrolizumab MK-3475-611/Keynote-611 — Completed
• ITIL-168 in Advanced Melanoma — Stopped early
• Clinical Trial of Neoadjuvant Chemotherapy With Atezolizumab or Placebo in Patients With Triple-Negative Breast Cancer Followed After Surgery by Atezolizumab or Placebo — Running, not enrolling
• ROMAN: Phase 3 Trial Investigating the Effects of GC4419 on Radiation Induced Oral Mucositis in Head/Neck Cancer Patients — Completed
• Study of Intraoperative Radiotherapy for Patients With Large Brain Metastases Treated With Neurosurgical Resection — Stopped early
• Consolidation Pembrolizumab Following Chemoradiation in Patients With Inoperable/Unresectable Stage III NSCLC — Completed
• Lintuzumab-Ac225 in Older Acute Myeloid Leukemia (AML) Patients — Completed
• ASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung Cancer — Stopped early
• Phase II (Treatment) Study of Oxaliplatin and Capecitabine in Advanced Head and Neck Malignancies — Completed
• Optimization of Smoking Cessation Strategies Concurrent With Treatment of Tobacco Related Malignancies — Completed
• Study of Autologous Tumor Infiltrating Lymphocytes (LN-145) In Combo With Durvalumab in Non-Small Cell Lung Cancer — Withdrawn before enrolling
• Safety and Tolerability Study of ISIS EIF4E Rx in Combination With Carboplatin and Paclitaxel — Completed
• Side Effects Involving the Heart in Women With Breast Cancer Receiving Doxorubicin and Trastuzumab — Completed
• A Randomized Phase IIb Placebo-Controlled Study of R-ICE Chemotherapy With and Without SGN-40 for Patients With DLBCL — Stopped early
• Phase II Study of AS1411 Combined With Cytarabine to Treat Acute Myeloid Leukemia — Completed